Cytokinesis: Does Mid1 Have an Identity Crisis?

Cytokinesis: Does Mid1 Have an Identity Crisis?

New work shows the anillin-related protein Mid1 does not position the cytokinetic ring in the fission yeast Schizosaccharomyces japonicus, unlike its role in S. pombe. Further analysis suggests the conserved function of Mid1-like anillin proteins may be in scaffolding, not positioning, the cytokinetic ring.

Cytokinesis: ER Keeps Mid1 in the Middle

How cells mark the region of the plasma membrane where the cleavage furrow will assemble is a classic question in cell biology. A new study has shown an unexpected role for cortically associated endoplasmic reticulum in positioning the site of cell division.

Identity crisis?

This article responds to arguments made in a recent paper by Bucholtz and Hall (Bucholtz, M., Hall, K., 2004. Theorizing identity in language and sexuality research. Language in Society 33, 469–515), in which two contrasting approaches to language and sexuality, dubbed ‘‘identity-based’’ and ‘‘desire-centered’’, are identified, and the latter is critiqued. As well as seeking to correct some ina...

Oncolytic Viruses: Therapeutics With an Identity Crisis

Oncolytic viruses (OV) are replicating viral therapeutics for the treatment of cancer and have been in laboratory development for about twenty years. Recently, the FDA approved Imlygic, a herpes virus based therapeutic for the treatment of melanoma and thus OVs have entered a new era where they are a weapon in the armament of the oncologist. OVs are unique therapeutics with multiple mechanisms ...

Are we having an identity crisis?